Modifications of lymphocyte subsets in autoimmune thrombocytopenic purpura patients submitted to splenectomy.

نویسندگان

  • M G Mazzucconi
  • P Piola
  • M C Arista
  • L Bizzoni
  • A Antenucci
  • L Conti
چکیده

1. Matutes E, Keeling DM, Newland AC, et al. Sezary celllike leukemia: a distinct type of mature T cell malignancy. Leukemia 1990; 4:262-6. 2. Pawson R, Matutes E, Brito-Babapulle V, et al. Sezary cell leukaemia: a distintc T cell disorder or a variant form of T prolymphocytic leukaemia? Leukemia 1997; 11:1009-13. 3. Garand R, Goasguen J, Brizard A, et al. Indolent course as a relatively frequent presentation in T-prolymphocytic leukaemia. Groupe Francais d’Hematologie Cellulaire. Br J Haematol 1998;103:488-94. 4. Harris NL, Jaffe ES, Diebold J, et al. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues:report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997. J Clin Oncol 1999; 17: 3835-49. 5. Matutes E, Brito-Babapulle V, Swansbury J, et al. Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia. Blood 1991; 78:3269-74. 6. Huhn D, Thiel E, Rodt H, Schlimok G, Theml H, Rieber P. Subtypes of t-cell chronic lymphatic leukemia. Cancer 1983; 51:1434-47. 7. Brito-Babapulle V, Pomfret M, Matutes E, Catovsky D. Cytogenetic studies on prolymphocytic leukemia. II. T-cell prolymphocytic leukemia. Blood 1987; 70:92631. 8. Brito-Babapulle V, Catovsky D. Inversions and tandem translocations involving chromosome 14q11 and 14q32 in T-prolymphocytic leukemia and T-cell leukemias in patients with ataxia telangiectasia. Cancer Genet Cytogen 1991; 55:1-9. 9. Maljaei SH, Brito-Babapulle V, Hiorns LR, Catovsky D. Abnormalities of chromosomes 8, 11, 14, and X in Tprolymphocytic leukemia studied by fluorescence in situ hybridization. Cancer Genet Cytogen 1998; 103: 110-6. 10. Mossafa H, Brizard A, Huret JL, et al. Trisomy 8q due to i(8q) or der(8) t(8;8) is a frequent lesion in T-prolymphocytic leukaemia: four new cases and a review of the literature. Br J Haematol 1994; 86:780-5.

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A Study of Epidemiology and Therapeutic Response of Patients with Immune Thrombocytopenic Purpura

Background: Immune thrombocytopenic purpura (ITP) is a disease characterized by decrease of the peripheral blood platelet count. The disease presents in acute and chronic forms. Because of the importance and high prevalence of ITP, it was decided to study the therapeutic response of patients with ITP. Material and Methods: A cross-sectional study was conducted at Ghaem hospital, Mashhad, Ira...

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Background: Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive platelet function disorder which is commonly mistaken for idiopathic thrombocytopenic purpura (ITP).The report includes seven cases of BSS that have been diagnosed and treated as ITP for a long time. Methods: Between 2006 and 2016, data of seven BSS patients who have long been diagnosed and treated as ITP were collected ...

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Comparative Study of Patients that Underwent Splenectomy for Immune Thrombocytopenic Purpura With and Without Splenic Artery Embolization

Basis and Objectives: Platelets and/or red blood cells transfusion usually are performed in patients with Immune Thrombocytopenic Purpura (ITP) who are submitted to splenectomy. The purpose of this study is to test if preoperative embolization of splenic artery is able to prevent platelets and/or red blood cells transfusion. Patients and Methods: All patients submitted to splenectomy for purpur...

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Rituximab responsive immune thrombocytopenic purpura in an adult with underlying autoimmune lymphoproliferative syndrome due to a splice-site mutation (IVS7+2 T>C) affecting the Fas gene

A 36 yr-old man of Israeli descent with a history of childhood splenectomy for severe thrombocytopenia and a family history of autoimmune lymphoproliferative syndrome (ALPS), presented with severe immune thrombocytopenic purpura refractory to standard therapy. He was found to possess a heterozygous mutation in the Fas gene (also termed TNFRSF6, CD95, Apo-1) affecting the donor splice site of in...

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Postsplenectomy Recurrence of Thrombocytopenia with an Accessory Spleen

Autoimmune thrombocytopenic purpura (AITP) is an autoimmune disorder that results from antiplatelet autoantibodies; these autoantibodies cause platelet destruction in the reticluoendothelial system. Oral corticosteroid therapy is the first line treatment. Splenectomy is the major treatment modality after the failure of more conservative medical therapy. Approximately 15% of the patients will re...

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عنوان ژورنال:
  • Haematologica

دوره 85 7  شماره 

صفحات  -

تاریخ انتشار 2000